At Hub South America, we focus on the Madre de Dios region in the Peruvian Amazon, an area facing significant landscape changes due to unsustainable activities such as agriculture expansion, logging and mining, exacerbated by the presence of an interoceanic highway. These changes pose threats to the biodiversity, local culture, and the well-being of Madre de Dios's inhabitants. To reverse these negative trends, in the Hub South America, we collaborate with partners to combine conservation with community needs, designing experiments based on scientific and local knowledge. Our aim is to establish new models and provide alternatives to the current development process, engaging in projects related to Innovative Territorial Governance, Transformative Knowledge Dialogues, and Active Networks for Transformative Change.